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  1. Uncertainty and Risk-Taking in Science
    Meaning, Measurement and Management
    Autor*in: Franzoni, Chiara; Stephan, Paula E.
    Erschienen: 2021
    Verlag:  National Bureau of Economic Research, Cambridge, Mass

    An underlying rationale for public support of science is that private companies underinvest in research of a risky nature. Yet, risk in science is a poorly understood concept. This paper sets out the foundations for understanding, measuring and... mehr

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    Sächsische Landesbibliothek - Staats- und Universitätsbibliothek Dresden
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    keine Fernleihe

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    Universitätsbibliothek Freiburg
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    Helmut-Schmidt-Universität, Universität der Bundeswehr Hamburg, Universitätsbibliothek
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    Staats- und Universitätsbibliothek Hamburg Carl von Ossietzky
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    Technische Informationsbibliothek (TIB) / Leibniz-Informationszentrum Technik und Naturwissenschaften und Universitätsbibliothek
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    ZBW - Leibniz-Informationszentrum Wirtschaft, Standort Kiel
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    An underlying rationale for public support of science is that private companies underinvest in research of a risky nature. Yet, risk in science is a poorly understood concept. This paper sets out the foundations for understanding, measuring and managing risk in science. We review insights offered from existing fields that study risk. These contributions, combined with knowledge gained from studies of science, are used to build a conceptual model of risk in science. The model is illustrated with examples drawn from the development of the IceCube Neutrino Observatory. It disentangles different components that determine risk and is used to operationalize an expert-based risk metric, potentially useful in peer review. Moreover, we review emerging empirical work on risk-taking in science, most of which suggests that the current reward structure of science discourages risky research. We develop and outline strategies for hedging and encouraging risk taking. We conclude by proposing a rich agenda for future studies, which is both intellectually challenging and critical for the future of science

     
    Export in Literaturverwaltung   RIS-Format
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    Quelle: Verbundkataloge
    Sprache: Englisch
    Medientyp: Buch (Monographie)
    Format: Online
    Weitere Identifier:
    Schriftenreihe: NBER working paper series ; no. w28562
    Schlagworte: Grundlagenforschung; Risiko
    Umfang: 1 Online-Ressource, illustrations (black and white)
    Bemerkung(en):

    Hardcopy version available to institutional subscribers
  2. The Repeated Setbacks of HIV Vaccine Development Laid the Groundwork for SARS-CoV-2 Vaccines
    Autor*in: Harris, Jeffrey E.
    Erschienen: 2021
    Verlag:  National Bureau of Economic Research, Cambridge, Mass

    The decades-long effort to produce a workable HIV vaccine has hardly been a waste of public and private resources. To the contrary, the scientific know-how acquired along the way has served as the critical foundation for the development of vaccines... mehr

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    Verlag (kostenfrei)
    Resolving-System (kostenfrei)

    Standort:
    Sächsische Landesbibliothek - Staats- und Universitätsbibliothek Dresden
    Fernleihe:
    keine Fernleihe

    Standort:
    Universitätsbibliothek Freiburg
    Fernleihe:
    keine Fernleihe

    Standort:
    Helmut-Schmidt-Universität, Universität der Bundeswehr Hamburg, Universitätsbibliothek
    Fernleihe:
    keine Fernleihe

    Standort:
    Staats- und Universitätsbibliothek Hamburg Carl von Ossietzky
    Fernleihe:
    keine Fernleihe

    Standort:
    Technische Informationsbibliothek (TIB) / Leibniz-Informationszentrum Technik und Naturwissenschaften und Universitätsbibliothek
    Fernleihe:
    keine Fernleihe

    Standort:
    ZBW - Leibniz-Informationszentrum Wirtschaft, Standort Kiel
    Fernleihe:
    keine Fernleihe

     

    The decades-long effort to produce a workable HIV vaccine has hardly been a waste of public and private resources. To the contrary, the scientific know-how acquired along the way has served as the critical foundation for the development of vaccines against the novel, pandemic SARS-CoV-2 virus. We retell the real-world story of HIV vaccine research - with all its false leads and missteps - in a way that sheds light on the current state of the art of antiviral vaccines. We find that HIV-related R&D had more than a general spillover effect. In fact, the repeated failures of HIV vaccine trials have served as a critical stimulus to the development of successful vaccine technologies today. We rebut the counterargument that HIV vaccine development has been no more than a blind alley, and that recently developed vaccines against COVID-19 are really descendants of successful vaccines against Ebola, MERS, SARS-CoV-1 and human papillomavirus. These successful vaccines likewise owe much to the vicissitudes of HIV vaccine development

     
    Export in Literaturverwaltung   RIS-Format
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    Quelle: Verbundkataloge
    Sprache: Englisch
    Medientyp: Buch (Monographie)
    Format: Online
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    Schriftenreihe: NBER working paper series ; no. w28587
    Schlagworte: AIDS; Impfung; Grundlagenforschung; Infektionskrankheit; Coronavirus
    Umfang: 1 Online-Ressource, illustrations (black and white)
    Bemerkung(en):

    Hardcopy version available to institutional subscribers
  3. Motives and Functions of Patenting in Public Basic Science
    Autor*in: Neumann, Michael
    Erschienen: 2021
    Verlag:  Springer Fachmedien Wiesbaden, Wiesbaden

    Export in Literaturverwaltung   RIS-Format
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    Quelle: Verbundkataloge
    Sprache: Englisch
    Medientyp: Ebook
    Format: Online
    ISBN: 9783658331221
    Weitere Identifier:
    9783658331221
    Auflage/Ausgabe: 1st edition 2021
    Schlagworte: Grundlagenforschung; Forschungsförderung; Öffentliche Förderung; Patentschutz; Technologietransfer; Grundlagenforschung; Patent; Anreiz; Wissenschaftler; Wissenschaftlerin; Motivation; Technologiepolitik; Gemeineigentum; Governance; Signaling; Theorie
    Weitere Schlagworte: (stw)Grundlagenforschung; (stw)Patent; (stw)Anreiz; (stw)Wissenschaftler; (stw)Motivation; (stw)Technologiepolitik; (stw)Gemeingüter; (stw)Governance-Ansatz; (stw)Signalling; (stw)Theorie; (stw)Deutschland; (Produktform)Electronic book text; (BISAC Subject Heading)BUS042000; (BISAC Subject Heading)KJ; (BISAC Subject Heading)BUS010000; (BISAC Subject Heading)SOC026000; (BIC subject category)LNC; (BIC subject category)JHB; publicly funded basic research; technology transfer; Third Mission; patenting motives; self-governed academic communities; (Springer Nature Marketing Classification)C; (Springer Nature Subject Code)SC500000: Business and Management, general; (Springer Nature Subject Code)SC529000: Business Law; (Springer Nature Subject Code)SCX22270: Science and Technology Studies; (Springer Nature Taxonomy)4071: Innovation and Technology Management; (Springer Nature Taxonomy)6248: Business Law; (Springer Nature Taxonomy)3231: Science, Technology and Society; (Springer Nature Subject Collection)SUCO41169: Business and Management; (lcsh)Business.; (lcsh)Management science.; (lcsh)Commercial law.; (lcsh)TechnologySociological aspects.
    Umfang: Online-Ressource