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  1. The motivational impact of nicotine and its role in Tobacco use
    Published: 2009
    Publisher:  Springer-Verlag, New York, NY

    More and more scientists are applying the concepts of motivation and related constructs to modify the behavior of drug-addicted and dependent people. Here, authors discuss effective 'translational' strategies for decreasing and preventing tobacco... more

    Location:
    Universität Potsdam, Universitätsbibliothek
    Inter-library loan:
    Unlimited inter-library loan, copies and loan

     

    More and more scientists are applying the concepts of motivation and related constructs to modify the behavior of drug-addicted and dependent people. Here, authors discuss effective 'translational' strategies for decreasing and preventing tobacco use. The Motivational Impact of Nicotine and its Role in Tobacco Use draws upon research on the drug widely believed to form the basis of tobacco use and dependence, nicotine. When discussing drug addiction and dependence, an increasing number of scientists are using the concepts of motivation and related constructs (e.g., incentive processes, cravings, drug seeking, etc.) and their applications in modifying behavior. The chapter authors discuss effective strategies for decreasing tobacco use and preventing initiation through a translational approach in which genetic, neurobiological, individual, and cultural factors motivating tobacco use and nicotine dependence are considered.

     
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    Content information
    Volltext (lizenzpflichtig)
    Source: Union catalogues
    Language: English
    Media type: Ebook
    Format: Online
    ISBN: 9780387787497
    Other identifier:
    RVK Categories: CW 6940
    Series: Nebraska symposium on motivation ; 55
    Subjects: Consciousness; Philosophy (General); Nicotine; Motivation; Tobacco Use Disorder
    Scope: Online-Ressource (XII, 212 S.)
    Notes:

    Includes bibliographical references and index

    Electronic reproduction; Available via World Wide Web

    Preface; Contributors; Contents; to 1 Nicotine, Tobacco Use, and the 55th Nebraska Symposium on Motivation; to 2 Synaptic Plasticity Within Midbrain Dopamine Centers Contributes to Nicotine Addiction; Introduction to the Health Problem; Midbrain Dopaminergic Systems; Action of Nicotine at Nicotinic Receptors in the Midbrain; Nicotine Influences Over Midbrain Synaptic Function; to 3 Molecular Mechanisms Underlying the Motivational Effects of Nicotine; Introduction; Cues and Nicotine Dependence; Prior Chronic Nicotine Exposure Enhances Conditioned Reinforcement

    Desensitization of nAChRs May Underlie the Ability of Nicotine to Enhance Cue SalienceBrain Areas Important for Nicotine's Effects on Cue Responding; Role of DA in Nicotine-Mediated Behaviors; nAChR Subtypes Involved in Modulating the DA System; Intracellular Signaling Downstream of nAChRs; Conclusions; to 4 Targeting Reward-Relevant Nicotinic Receptors in the Discovery of Novel Pharmacotherapeutic Agents to Treat Tobacco Dependence; Introduction; Tobacco Alkaloids and Tobacco Use; Nicotinic Receptor-Mediated Dopamine Release in Nicotine Reward; Nicotinic Receptor Subtypes; nAChR Antagonists

    Approved Smoking Cessation PharmacotherapiesNovel nAChR Antagonists; Methods; Animals; Synthesis of Analogs; [ 3 H]DA Release Assay; Nicotine-Induced Reinstatement of Nicotine Self-Administration; Results and Discussion; [ 3 H]DA Release Assay; Nicotine-Induced Reinstatement of Nicotine Self-Administration; to 5 Multiple Motivational Forces Contribute to Nicotine Dependence; Introduction; Rewarding Effects of Nicotine; Primary Rewarding Effects of Nicotine; Conditioned Rewarding Effects of Stimuli Associated with Nicotine Administration; Reward-Enhancing Effects of Nicotine

    Primary Reward-Enhancing Effects of NicotineConditioned Reward-Enhancing Effects of Psychomotor Stimulants; Nicotine Withdrawal; Decreased Brain Reward Function during Nicotine Withdrawal; The Somatic Aspects of Nicotine Withdrawal; Motivational Significance of Anhedonic Versus Somatic Components of Drug Withdrawal; Conditioned Nicotine Withdrawal; Cognitive-Enhancing Effects of Nicotine; Conclusions; to 6 The Role of Nicotine in Smoking: A Dual-Reinforcement Model; Introduction; Role of Non-Nicotine Stimuli in Self-Administration and Smoking; Dual Reinforcing Effects of Nicotine

    Predictions of the Dual-Reinforcement Model: Reinforcing Strength of the Nonpharmacological StimulusPredictions of the Dual-Reinforcement Model: Behavioral Dissociation; Predictions of the Dual-Reinforcement Model: Pharmacological Dissociation; Predictions of the Dual-Reinforcement Model: Role of Conditioning; Nature and Temporal Dynamics of Nicotine's Reinforcement-Enhancing Effects; Significance of the Dual-Reinforcement Model; Summary and Conclusions; to 7 Altering the Motivational Function of Nicotine through Conditioning Processes; Introduction; Nicotine as a Reinforcer

    Nicotine as a Discriminative Stimulus
  2. The motivational impact of nicotine and its role in tobacco use
    Published: 2009
    Publisher:  Springer, New York, NY

    Location:
    Universitätsbibliothek Bamberg
    Inter-library loan:
    Unlimited inter-library loan, copies and loan

    Location:
    Universitätsbibliothek Regensburg
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    Unlimited inter-library loan, copies and loan

    Location:
    Hochschule für angewandte Wissenschaften Würzburg-Schweinfurt, Abteilungsbibliothek Schweinfurt
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    Unlimited inter-library loan, copies and loan

    Location:
    Technische Hochschule Würzburg-Schweinfurt Bibliothek
    Inter-library loan:
    Unlimited inter-library loan, copies and loan

    Location:
    Universitätsbibliothek Würzburg
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    Unlimited inter-library loan, copies and loan
    Export to reference management software   RIS file
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    Content information
    Source: Union catalogues
    Language: English
    Media type: Ebook
    Format: Online
    ISBN: 0387787488; 9780387787497
    Other identifier:
    9780387787480
    RVK Categories: CW 6940
    Series: Nebraska Symposium on Motivation ; 55
    Subjects: Nicotin; Suchtgefährdung; Rauchen; Motivation
    Scope: 1 Online-Ressource
  3. The motivational impact of nicotine and its role in Tobacco use
    Published: 2009
    Publisher:  Springer-Verlag, New York, NY

    More and more scientists are applying the concepts of motivation and related constructs to modify the behavior of drug-addicted and dependent people. Here, authors discuss effective 'translational' strategies for decreasing and preventing tobacco... more

    Location:
    Staats- und Universitätsbibliothek Hamburg Carl von Ossietzky
    Inter-library loan:
    No inter-library loan

    Location:
    Otto-von-Guericke-Universität, Universitätsbibliothek
    Signature:
    eBook Springer
    Inter-library loan:
    No inter-library loan

    Location:
    Otto-von-Guericke-Universität, Universitätsbibliothek, Medizinische Zentralbibliothek
    Signature:
    eBook Springer
    Inter-library loan:
    No inter-library loan

    Location:
    Universität Potsdam, Universitätsbibliothek
    Inter-library loan:
    No inter-library loan

     

    More and more scientists are applying the concepts of motivation and related constructs to modify the behavior of drug-addicted and dependent people. Here, authors discuss effective 'translational' strategies for decreasing and preventing tobacco use. The Motivational Impact of Nicotine and its Role in Tobacco Use draws upon research on the drug widely believed to form the basis of tobacco use and dependence, nicotine. When discussing drug addiction and dependence, an increasing number of scientists are using the concepts of motivation and related constructs (e.g., incentive processes, cravings, drug seeking, etc.) and their applications in modifying behavior. The chapter authors discuss effective strategies for decreasing tobacco use and preventing initiation through a translational approach in which genetic, neurobiological, individual, and cultural factors motivating tobacco use and nicotine dependence are considered.

     
    Export to reference management software   RIS file
      BibTeX file
    Content information
    Volltext (lizenzpflichtig)
    Source: Union catalogues
    Language: English
    Media type: Ebook
    Format: Online
    ISBN: 9780387787497
    Other identifier:
    RVK Categories: CW 6940
    Series: Nebraska symposium on motivation ; 55
    Subjects: Consciousness; Philosophy (General); Nicotine; Motivation; Tobacco Use Disorder
    Scope: Online-Ressource (XII, 212 S.)
    Notes:

    Includes bibliographical references and index

    Electronic reproduction; Available via World Wide Web

    Preface; Contributors; Contents; to 1 Nicotine, Tobacco Use, and the 55th Nebraska Symposium on Motivation; to 2 Synaptic Plasticity Within Midbrain Dopamine Centers Contributes to Nicotine Addiction; Introduction to the Health Problem; Midbrain Dopaminergic Systems; Action of Nicotine at Nicotinic Receptors in the Midbrain; Nicotine Influences Over Midbrain Synaptic Function; to 3 Molecular Mechanisms Underlying the Motivational Effects of Nicotine; Introduction; Cues and Nicotine Dependence; Prior Chronic Nicotine Exposure Enhances Conditioned Reinforcement

    Desensitization of nAChRs May Underlie the Ability of Nicotine to Enhance Cue SalienceBrain Areas Important for Nicotine's Effects on Cue Responding; Role of DA in Nicotine-Mediated Behaviors; nAChR Subtypes Involved in Modulating the DA System; Intracellular Signaling Downstream of nAChRs; Conclusions; to 4 Targeting Reward-Relevant Nicotinic Receptors in the Discovery of Novel Pharmacotherapeutic Agents to Treat Tobacco Dependence; Introduction; Tobacco Alkaloids and Tobacco Use; Nicotinic Receptor-Mediated Dopamine Release in Nicotine Reward; Nicotinic Receptor Subtypes; nAChR Antagonists

    Approved Smoking Cessation PharmacotherapiesNovel nAChR Antagonists; Methods; Animals; Synthesis of Analogs; [ 3 H]DA Release Assay; Nicotine-Induced Reinstatement of Nicotine Self-Administration; Results and Discussion; [ 3 H]DA Release Assay; Nicotine-Induced Reinstatement of Nicotine Self-Administration; to 5 Multiple Motivational Forces Contribute to Nicotine Dependence; Introduction; Rewarding Effects of Nicotine; Primary Rewarding Effects of Nicotine; Conditioned Rewarding Effects of Stimuli Associated with Nicotine Administration; Reward-Enhancing Effects of Nicotine

    Primary Reward-Enhancing Effects of NicotineConditioned Reward-Enhancing Effects of Psychomotor Stimulants; Nicotine Withdrawal; Decreased Brain Reward Function during Nicotine Withdrawal; The Somatic Aspects of Nicotine Withdrawal; Motivational Significance of Anhedonic Versus Somatic Components of Drug Withdrawal; Conditioned Nicotine Withdrawal; Cognitive-Enhancing Effects of Nicotine; Conclusions; to 6 The Role of Nicotine in Smoking: A Dual-Reinforcement Model; Introduction; Role of Non-Nicotine Stimuli in Self-Administration and Smoking; Dual Reinforcing Effects of Nicotine

    Predictions of the Dual-Reinforcement Model: Reinforcing Strength of the Nonpharmacological StimulusPredictions of the Dual-Reinforcement Model: Behavioral Dissociation; Predictions of the Dual-Reinforcement Model: Pharmacological Dissociation; Predictions of the Dual-Reinforcement Model: Role of Conditioning; Nature and Temporal Dynamics of Nicotine's Reinforcement-Enhancing Effects; Significance of the Dual-Reinforcement Model; Summary and Conclusions; to 7 Altering the Motivational Function of Nicotine through Conditioning Processes; Introduction; Nicotine as a Reinforcer

    Nicotine as a Discriminative Stimulus
  4. The Motivational Impact of Nicotine and its Role in Tobacco Use
    Author: Caggiula, Anthony R.
    Published: 2009
    Publisher:  Springer US, New York, NY

    Location:
    Technische Universität Chemnitz, Universitätsbibliothek
    Inter-library loan:
    No inter-library loan

    Location:
    Zeppelin Universität gGmbH, Bibliothek
    Inter-library loan:
    No inter-library loan

    Location:
    Hochschule Furtwangen University. Informatik, Technik, Wirtschaft, Medien. Campus Furtwangen, Bibliothek
    Signature:
    eBook Springer
    Inter-library loan:
    No inter-library loan
    Export to reference management software   RIS file
      BibTeX file
    Content information
    Source: Union catalogues
    Language: English
    Media type: Ebook
    Format: Online
    ISBN: 9780387787497
    Other identifier:
    RVK Categories: CW 6940 ; MR 6100
    Series: Nebraska Symposium on Motivation ; 55
    Array
    Subjects: Philosophy (General); Consciousness; Psychology; Nicotine addiction; Tobacco use; Motivation (Psychology)
    Scope: Online-Ressource (digital)